Non-Productive Pathways During Initiation Phase of RNA Transcription: Abortive and Antisense Transcription

The scientific definition of RNA transcription is the process through which “a DNA sequence is enzymatically copied by an RNA polymerase to produce a complementary RNA”. It is well-established in academic literature that RNAP is relatively error-prone. This paper will introduce two cases that reflect the inherently low accuracy of the RNAP through separate mechanisms: the abortive and antisense transcription.